35959-08-1

Usage

Uses

Used in Pharmaceutical Industry:
3β-Acetoxy-13-hydroxyurs-11-ene-28-oic acid lactone is used as a potential therapeutic agent for [application reason] due to its classification as a triterpenoid, which is a class of compounds known for their diverse biological activities. Further research is required to explore its specific therapeutic benefits and establish its safety profile.
Used in Chemical Industry:
3β-Acetoxy-13-hydroxyurs-11-ene-28-oic acid lactone is used as a chemical intermediate for [application reason] in the synthesis of various compounds. Its unique structure and properties may offer advantages in the development of new chemical products, pending further investigation into its reactivity and stability.
Note: Since the provided materials do not specify the exact applications or reasons for using 3β-Acetoxy-13-hydroxyurs-11-ene-28-oic acid lactone, the placeholders [application reason] are used to indicate that further information is needed to complete the uses section accurately.

Upstream product

• 915-79-7 (3β)-3-acetoxy-urs-12-en-28-carboxylic acid 
• 108-24-7 acetic anhydride 
• 35959-05-8 ursolic acid lactone 

Relevant academic research and scientific papers

Oxyfunctionalization products of terpenoids with dimethyldioxirane and their biological activity

Oxyfunctionalization of the bioactive terpenoids, ursolic acid acetate (1), oleanolic acid acetate (5), lupeol acetate (12), and kaurenic acid (17), with dimethyldioxirane (DMDO) was investigated. Treatment of the terpenoids with DMDO under mild conditions afforded a variety of oxidation and oxydegradation products to yield naturally occurring and/or novel compounds in one step. After chromatographic separation, the structures of the individual isolated products were determined using spectroscopic methods including several homonuclear ( 1H-1H) and heteronuclear (1H-13C) shift-correlated 2D-NMR techniques. The inhibitory activity of the terpenoid derivatives against α-glucosidase was investigated and compounds 1, 3, 7, and 9 were found to exhibit potent activity.

Stereochemistry of hydrogen peroxide - Acetic acid oxidation of ursolic acid and related compounds

Stereochemistry of a number of oxidized derivatives or ursolic acid was established using NMR data and X-ray analysis. Full signal assignments were made in 1H and 13C NMR spectra of 26 natural and synthetic ursane type triterpenoids. Possible mechanisms of oxidation of ursolic acid and related compounds by peracids, as well as mechanisms of secondary processes, were formulated basing on chemical behavior and molecular mechanics calculations of the starting materials and certain intermediate species.

Phase-transfer Catalysed Sodium Periodate Oxidation of Ursolic Acid and Oleanolic Acid Derivatives: An Efficient and General Method for the Syntheses of 11-en-13β,28-Olides

Sodium periodate oxidation of oleanolic acid and ursolic acid derivatives under phase-transfer catalysis furnishes the corresponding 11-en-13β,28-olides in excellent yields.Syntheses of Δ11-ursolic lactone acetate (1) and triacetyl dryobalanolide (2) using this reagent are described.