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2',5'-Dideoxyuridine, a synthetic analog of the nucleoside uridine, is a compound that plays a significant role in molecular biology and biochemistry research. It is characterized by the absence of a 3'-hydroxyl group, which is crucial for the addition of subsequent nucleotides during DNA replication. This unique feature allows 2',5'-dideoxyuridine to terminate DNA synthesis, making it a valuable tool for studying the mechanism of DNA polymerases.

35959-50-3

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35959-50-3 Usage

Uses

Used in Research Applications:
2',5'-Dideoxyuridine is used as a research tool for studying the mechanism of DNA polymerases, as its absence of a 3'-hydroxyl group prevents the addition of subsequent nucleotides during DNA replication, thereby terminating DNA synthesis.
Used in Antiviral Applications:
In the field of antiviral research, 2',5'-dideoxyuridine has been explored for its potential activity against certain DNA viruses, such as herpes simplex virus and cytomegalovirus. It achieves this by inhibiting the DNA polymerase activity of these viruses, which is essential for their replication.
Used in Cancer Treatment Research:
2',5'-Dideoxyuridine has also been investigated for its potential use in cancer treatment. Its ability to inhibit DNA synthesis and cell proliferation makes it a promising candidate for therapeutic intervention in cancer cells, offering a possible avenue for the development of novel cancer therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 35959-50-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,9,5 and 9 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 35959-50:
(7*3)+(6*5)+(5*9)+(4*5)+(3*9)+(2*5)+(1*0)=153
153 % 10 = 3
So 35959-50-3 is a valid CAS Registry Number.

35959-50-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]pyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names 2'-5'dideoxyuridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35959-50-3 SDS

35959-50-3Upstream product

35959-50-3Downstream Products

35959-50-3Relevant academic research and scientific papers

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