359631-35-9

Basic information

• Product Name: 5-Oxazolecarboxylicacid,2-amino-4-methyl-,methylester(9CI)
• Synonyms: 5-Oxazolecarboxylicacid,2-amino-4-methyl-,methylester(9CI);Methyl 2-amino-4-methyl-1,3-oxazole-5-carboxylate;Methyl 2-amino-4-methyloxazole-5-carboxylate
• CAS NO: 359631-35-9
• Molecular Formula: C6H8N2O3
• Molecular Weight: 156.14
• Product Categories: CARBOXYLICESTER
• Mol File: 359631-35-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Oxazolecarboxylicacid,2-amino-4-methyl-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Oxazolecarboxylicacid,2-amino-4-methyl-,methylester(9CI)(359631-35-9)
• EPA Substance Registry System: 5-Oxazolecarboxylicacid,2-amino-4-methyl-,methylester(9CI)(359631-35-9)

Safety Data

• Hazardous Substances Data: 359631-35-9(Hazardous Substances Data)

Upstream product

• 4755-81-1 methyl 2-chloroacetoacetate 
• 57-13-6 urea 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING

Provided herein are compounds having activity against TTR related conditions, and pharmaceutically accepted salts and solvates thereof. Also provided are methods of using the compounds for inhibiting and preventing TTR aggregation and/or amyloid formation in the peripheral nerves, kidney, cardiac tissue, eye and CNS, and of treating a subject with peripheral TTR amyloidosis.

Oxazoles and their agricultural compositions

A compound having the formula R--S(O)n CH2 CH2 CH=CF2, wherein R is a phenyl group or a heterocyclic group selected from furyl, thienyl, isoxazolyl, isothiazolyl, oxazolyl, thiazolyl, imidazolyl, pyrazolyl, 1,2,4-oxadiazolyl, 1,2,4-thiadiazolyl, 1,3,4-oxadiazolyl, 1,3,4-thidiazolyl, tetrazolyl, pyridyl, pyridazinyl, pyrazinyl, 1,2,3-triazinyl, 1,3,4-triazinyl, and 1,3,5-triazinyl groups, said phenyl or heterocyclic group being optionally substituted by optionally substituted alkyl, optionally substituted alkenyl, alkynyl, cycloalkyl, alkylcycloalkyl, alkoxy, alkenyloxy, alkynyloxy, hydroxyalkyl, alkoxyalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl, optionally substituted heteroarylalkyl, optionally substituted aryloxy, optionally substituted arylalkoxy, optionally substituted aryloxyalkyl, optionally substituted heteroaryloxy, optionally substituted heteroarylalkoxy, optionally substituted heteroaryloxyalkyl, haloalkyl, haloalkenyl, haloalkynyl, haloalkoxy, haloalkenyloxy, haloalkynyloxy, halogen, hydroxy, cyano, nitro, --NR7R8, --NR7COR8, --NR7CSR8, --NR7SO2R8, --N(SO2R7)(SO2R8), --COR7, --CONR7R8, -alkylCONR7R8, --CR7NR8, --COOR7, --OCOR7, --SR7, --SOR7, --SO2R7, -alkylSR7, -alkylSOR7, -alkylSO2R7, --OSO2R7, --SO2NR7R8, --CSNR7R8, --SiR7R8R9, --OCH2CO2R7, --OCH2CH2CO2R7, --CONR7SO2R8, -alkylCONR7SO2R8, --NHCONR7R8, --NHCSNR7R8, or an adjacent pair of R1, R2, R3, R4, R5 and R6 when taken together form a fused 5- or 6-membered carbocyclic or heterocyclic ring; R7, R8 and R9 are each independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl, alkynyl, optionally substituted aryl or optionally substituted arylalkyl, haloalkyl, haloalkenyl, haloalkynyl, halogen or hydroxy.