35970-80-0 Usage
General Description
4-HYDRAZINO-6-PHENYLTHIENO[2,3-D]PYRIMIDINE, also known as AG-120, is a chemical compound that has shown potential as a targeted therapy in the treatment of certain types of cancer, particularly those related to mutations in the isocitrate dehydrogenase 1 (IDH1) gene. It works by inhibiting the mutated IDH1 enzyme, which is involved in the production of oncometabolite 2-hydroxyglutarate (2-HG), believed to be a driver of tumorigenesis. AG-120 has been investigated in preclinical and clinical studies, showing promising results for the treatment of acute myeloid leukemia (AML) and other solid tumors. Further research and clinical trials are ongoing to explore the full potential of this compound in cancer therapy.
Check Digit Verification of cas no
The CAS Registry Mumber 35970-80-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,9,7 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 35970-80:
(7*3)+(6*5)+(5*9)+(4*7)+(3*0)+(2*8)+(1*0)=140
140 % 10 = 0
So 35970-80-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H10N4S/c13-16-11-9-6-10(8-4-2-1-3-5-8)17-12(9)15-7-14-11/h1-7H,13H2,(H,14,15,16)
