35977-17-4

Upstream product

• 622-78-6 Benzyl isothiocyanate 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 20776-50-5 2-amino-4-bromobenzoic acid 

Downstream Products

• 305804-86-8 3,4-dihydro-3-benzyl-6-bromo-2-hydrazino-quinazolin-4-one 
• 449211-07-8 4-Benzyl-5-oxo-4,5-dihydro-imidazo[1,2-a]quinazoline-7-carboxylic acid (benzo[1,3]dioxol-5-ylmethyl)-amide 
• 83390-32-3 2-(3-Benzyl-6-bromo-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl)-N-(5-cyclohexyl-[1,3,4]thiadiazol-2-yl)-acetamide 
• 83390-33-4 2-(3-Benzyl-6-bromo-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl)-N-[5-(2-cyclohexyl-ethyl)-[1,3,4]thiadiazol-2-yl]-acetamide 

Relevant academic research and scientific papers

1-Amino triazoloc4,3-a! quinazoline-5-ones and/or -5-thiones inhibiting phosphodiesterase IV

The present invention relates to triazolo[4,3-a]quinazoline-5-ones and 5-thiones of Formula I and Formula II, whereby I and II are position isomers of group R on nitrogen 3 or 4. Optionally, the invention also relates to the racemic forms, isomers and pha

Synthesis and evaluation of substituted quinazolone derivatives for antibacterial, antifungal, and antiacetylcholinesterase activities

The synthesis of new 6-bromo- and 6,8dibromo-2-[N-(2'-alkyl -1',3',4' -thiadiazol -5' -yl)carbamoylmethylthiol] -3- aryl/cyclohexyl-4-(3H)-quinazolones is described. The synthesized derivatives were screened for antibacterial, antifungal, and antiacetylcholinesterase activities in vitro. Most of the compounds exhibited significant biological activity. The relation between their biological activity and chemical structure was studied.