359773-61-8

Upstream product

• 202464-67-3 di-O-benzyl 4,6-O-diacetyl-3-O-((R)-phenylsulfonylethylpropion-2-yl)-N-acetyl-α-D-glucosamine-1-phosphate 
• 2862-03-5 Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(R)-1-carboxyethyl>-α-D-glucopyranoside 
• 73089-68-6 benzyl 2-acetamido-4,6-O-benzylidene-3-O-[(R)-1-carboxyethyl]-2-deoxy-α-D-glucopyranoside 
• 917029-90-4 benzyl 2-acetamido-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranoside 
• 359773-59-4 4,6-O-diacetyl-3-O-((R)-phenylsulfonylethyl-propion-2-yl)-N-acetyl-α-D-glucosamine 
• 202464-70-8 benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-(D-1-{[2-(phenylsulfonyl)ethoxy]carbonyl}ethyl)-α-D-glucopyranoside 
• 202464-71-9 1-O-benzyl-4,6-O-diacetyl-3-O-((R)-phenylsulfonylethyl-propion-2-yl)-N-acetyl-α-D-glucosamine 

Downstream Products

• 202464-73-1 C₅₃H₇₃F₃N₇O₂₁P 

Relevant academic research and scientific papers

The total synthesis of lipid I

A total synthesis of lipid I (4), a membrane-associated intermediate in the bacterial cell wall (peptidoglycan) biosynthesis pathway, is reported. This highly convergent synthesis will enable further studies on bacterial resistance mechanisms and may prov

Synthesis of P1-Citronellyl-P2-α-D-pyranosyl pyrophosphates as potential substrates for the E. coli undecaprenyl-pyrophosphoryl-N-acetylglucoseaminyl transferase MurG

P1-Citronellyl-P2-α-D-pyranosyl pyrophosphates containing α-D-N-acetylglucoseaminyl, α-D-glucosyl, and α-D-N-acetylmuramyl carbohydrates were synthesized and used in substrate specificity studies of the Escherichia coli MurG enzyme. Oxalyl chloride activation of citronellyl phosphate for coupling to α-D-pyranose-1-phosphates resulted in markedly improved yields over traditional Khorana-Moffatt and diphenyl chlorophosphate activation strategies.