3598-66-1

Usage

Uses

Used in Chemical Synthesis:
3-(2,6-Dichlorophenoxy)-1-propyne is used as a key intermediate in the production of various chemicals. Its reactivity allows it to participate in multiple chemical reactions, making it an essential building block in organic synthesis for creating a wide array of compounds.
Used in Agricultural Industry:
In the agricultural sector, 3-(2,6-Dichlorophenoxy)-1-propyne is used as a precursor in the synthesis of herbicides. Its role in creating effective weed control agents is crucial for enhancing crop yields and maintaining agricultural productivity.
Used in Industrial Applications:
3-(2,6-Dichlorophenoxy)-1-propyne also finds use in industrial applications, where it serves as a component in the manufacturing of insecticides. Its contribution to pest control helps protect various industries from the detrimental effects of insect infestations.

InChI:InChI=1/C9H6Cl2O/c1-2-6-12-9-7(10)4-3-5-8(9)11/h1,3-5H,6H2

Upstream product

• 87-65-0 2,6-Dichlorophenol 
• 106-96-7 propargyl bromide 

Downstream Products

• 1485823-19-5 C₁₆H₁₆Cl₂N₆O₃ 
• 1485822-10-3 4-((2,6-dichlorophenoxy)methyl)-1-(2-(1-methyl-5-nitro-1H-imidazol-2-yl)ethyl)-1H-1,2,3-triazole 
• 1485821-00-8 C₁₄H₁₂Cl₂N₆O₃ 
• 1485819-91-7 4-((2,6-dichlorophenoxy)methyl)-1-(2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl)-1H-1,2,3-triazole 
• 1335447-29-4 (7-chloroquinolin-4-yl)-{2-[4-(2,6-dichlorophenoxymethyl)-[1,2,3]triazol-1-yl]ethyl}amine 
• 1393738-17-4 C₂₇H₂₈Cl₂F₂N₄O₁₀ 

Relevant academic research and scientific papers

Bimetal-Catalyzed Cascade Reaction for Efficient Synthesis of N-Isopropenyl 1,2,3-Triazoles via In-Situ Generated 2-Azidopropenes

A bimetal-catalyzed cascade reaction for the synthesis of N-isopropenyl 1,2,3-triazoles in high yield is reported. This reaction involves the generation of 2-azidopropenes in situ by C(sp3)-OAr bond cleavage for click reaction and features a broad substrate scope, good functional group tolerance and readily available substrates.

Anti-methicillin resistant Staphylococcus aureus activity, synergism with oxacillin and molecular docking studies of metronidazole-triazole hybrids

MRSA causes 60-70% of Staphylococcus aureus infection in hospitals and it has developed resistance against the currently available drugs. Interestingly, a series of 35 metronidazole-triazole hybrids on screening against MRSA were found to be active. Compound 22 was found to be effective at 4 μg/mL concentration against nine strains of MRSA. The inhibitory activity was further enhanced upto 1 μg/mL when this compound was used in combination with oxacillin in 1:1 ratio. All the compounds were found to be non-toxic in THP-1 cell line upto a concentration of 50 μM. The time-kill kinetics studies suggested bacteriostatic nature of the compounds. In silico studies show that these compounds interact with Thr600, Ser598, Asn464, His583 and Tyr446 in the active site of PBP2a crystal structure from MRSA.

142. Thermal rearrangements of halogen substituted aryl propargyl ethers

7-Chloro-2-chloromethyl-benzofuran (13) and 3, 8-dichloro-2H-1-benzopyran (12) are the main products from the thermal rearrangement (230-260°) of 2, 6-dichlorophenyl propargyl ether (7). Compounds 17, 18 and 19 are also formed, but in much smaller amounts