359803-93-3

Upstream product

• 4521-28-2 4-(4-Methoxyphenyl)butyric acid 
• 7021-11-6 4-(4-hydroxyphenyl)butanoic acid 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 459867-15-3 (4-but-3-enyl-phenoxy)-tert-butyl-dimethyl-silane 
• 459867-16-4 4-(4-((tert-butyldimethylsilyl)oxy)phenyl)butan-1-ol 

Downstream Products

• 459867-16-4 4-(4-((tert-butyldimethylsilyl)oxy)phenyl)butan-1-ol 
• 459867-18-6 1-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-2-{4-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-butylamino}-ethanol 
• 130783-37-8 Arbutamine 
• 459867-17-5 N-{2-[3,4-bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-2-hydroxy-ethyl}-4-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-butyramide 

Relevant academic research and scientific papers

Total Synthesis of Tedarene A

Tedarene A is a macrocyclic diaryl ether heptanoid isolated from the marine sponge Tedania ignis showing an inhibitory effect against nitric oxide production. The first total synthesis of tedarene A was achieved starting from the commercially available 3-

Effect of ligand structure on the zinc-catalyzed Henry reaction. Asymmetric syntheses of (-)-denopamine and (-)-arbutamine

(Matrix presented) Syntheses of variously modified ligands for the dinuclear zinc catalysts for the asymmetric aldol and nitroaldol (Henry) reactions are reported. Catalytic enantioselective nitroaldol reactions promoted by these modified ligands led to efficient syntheses of the β-preceptor agonists (-)-denopamine and (-)-arbutamine.