359860-27-8

Basic information

• Product Name: N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE
• Synonyms: N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE;Biotin-PEG4-amine;(+)-Biotin-PEG3-CH2CH2NH2;(+)-Biotinyl 3,6,9-trioxaundecanediamine;(+)-Biotin-PEG3-amine;Biotin-PEG3-NH2;(+)-Biotinyl-3,6,9,-trioxaundecanediamine(Amine-PEG3-Biotin);N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
• CAS NO: 359860-27-8
• Molecular Formula: C₁₈H₃₄N₄O₅S
• Molecular Weight: 418.55
• Mol File: 359860-27-8.mol

Chemical Properties

• Boiling Point: 705.8±60.0 °C(Predicted)
• Appearance: /
• Density: 1.166±0.06 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: Methanol (Slightly)
• PKA: 13.90±0.40(Predicted)
• CAS DataBase Reference: N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE(359860-27-8)
• EPA Substance Registry System: N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE(359860-27-8)

Safety Data

• Hazardous Substances Data: 359860-27-8(Hazardous Substances Data)

Usage

Description

Biotin-PEG3-amine is reactive with NHS ester or carboxylic acid in the presence of EDC or HATU. PEG3 increases aqueous solubility of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Uses

(+)-Biotinyl 3,6,9-Trioxaundecanediamine is a biotin derivative and is used as a reagent in the synthesis of a potent, covalent BTK inhibitor for B-cell lymphoma.