359865-10-4

Upstream product

• 853092-57-6 5-(4-methoxy-phenyl)-4-(9-phenyl-9H-fluoren-9-ylamino)-pent-1-en-3-ol 
• 359865-05-7 3-(4-hydroxy-phenyl)-2-(9-phenyl-9H-fluoren-9-ylamino)-propionic acid methyl ester 
• 359865-07-9 3-(4-methoxy-phenyl)-2-(9-phenyl-9H-fluoren-9-ylamino)-propan-1-ol 
• 359865-06-8 3-(4-methoxy-phenyl)-2-(9-phenyl-9H-fluoren-9-ylamino)-propionic acid methyl ester 
• 3410-66-0 D-tyrosine methyl ester 
• 556-02-5 tyrosine 
• 359865-08-0 3-p-methoxyphenyl-2α-N-9-phenylfluoren-9-ylamino-1-propanal 
• 853092-38-3 (4R)-5-(p-methoxyphenyl)-4-(N-9-phenylfluoren-9-yl)aminopent-1-en-3-one 
• 359865-09-1 4α-N-9-phenylfluoren-9-ylamino-3α-hydroxy-5-p-methoxyphenyl-1-pentyne 

Downstream Products

• 853092-54-3 (2R,3S,4R)-N-(9-phenylfluoren-9-yl)deacetylanisomycin 
• 604789-37-9 (2R,3S,4R)-deacetylanisomycin 
• 359865-12-6 N-9-phenylfluoren-9-ylamino-3α-acetoxy-4α-iodo-2α-(p-methoxybenzyl)pyrrolidine 
• 359865-11-5 4α-N-9-phenylfluoren-9-ylamino-3α-acetoxy-5-p-methoxyphenyl-1-pentene 

Relevant academic research and scientific papers

Stereodivergent syntheses of anisomycin derivatives from D-tyrosine

Enantiomerically pure 2-alkyl-3-acetoxy-4-iodopyrrolidines with all groups cis, and all adjacent groups trans (10 and 17), important precursors for the synthesis of pyrrolidinediols, have been prepared from D-tyrosine through regio- and diastereoselective

Diastereoselective iodoamidation of 3-acetoxybut-1-Enylamines: Synthesis of 3-acetoxy-4-iodo-2-(p-methoxybenzyl)pyrrolidines

3α-Acetoxy-4α-iodo-2α-(p-methoxybenzyl)pyrrolidine (2) and its enanti-omer (3) were synthesized via diastereoselective iodoamidation, starting from D- or L-tyrosine. The key step contains unfavorable 5-endo-trig cyclization and the diastereoselective addition of ethynylmagnesium bromide to aldehydes (9) by the chelation-controlled Cram cyclic model.