35998-80-2Relevant academic research and scientific papers
Metal-free approach for the ?-proline mediated synthesis of nitrones from nitrosobenzene
Choi, Minho,Viji, Mayavan,Kim, Donghwan,Lee, Young Hee,Sim, Jaeuk,Kwak, Young-Shin,Lee, Kiho,Lee, Heesoon,Jung, Jae-Kyung
, p. 4182 - 4187 (2018)
An efficient, and metal-free approach for the ?-proline mediated synthesis of nitrones from nitrosobenzene and benzaldehydes has been established. The reaction undergoes very efficiently at room temperature in methanol as a solvent. The reaction is assumed to involve that the initial formation of azomethine ylide and [2 + 3] cycloaddition of nitrosobenzene, followed by the subsequent retro [2 + 3] cycloaddition could offer the desired nitrone.
Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF3S-Containing Isoxazolidines
Riesco-Domínguez, Alejandra,Van De Wiel, Jeroen,Hamlin, Trevor A.,Van Beek, Bas,Lindell, Stephen D.,Blanco-Ania, Daniel,Bickelhaupt, F. Matthias,Rutjes, Floris P. J. T.
, p. 1779 - 1789 (2018/02/23)
Trifluoromethyl vinyl sulfide, a potential building block for pharmaceutically and agrochemically relevant products, is prepared and used for the first time in high-pressure-mediated 1,3-dipolar cycloaddition reactions with nitrones to synthesize (trifluoromethyl)sulfanyl isoxazolidines.
