36002-67-2 Usage
Hetercyclic compound
It contains a ring structure with different types of atoms (carbon, nitrogen, and oxygen) bonded together.
Unique ring structure
The arrangement of atoms in the ring is specific, with a 1,2,4-oxadiazol and a quinoxalinone fused together.
Pharmaceuticals
It may have uses in the development of new drugs or drug candidates.
Organic synthesis
It can be used as a building block or intermediate in the synthesis of other complex organic molecules.
Research and development
It may be used in the study and development of new materials and substances, contributing to the advancement of various scientific fields.
Interesting and valuable
Due to its unique structure and potential applications, this compound is considered an interesting and valuable subject for further study and exploration.
Check Digit Verification of cas no
The CAS Registry Mumber 36002-67-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,0,0 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 36002-67:
(7*3)+(6*6)+(5*0)+(4*0)+(3*2)+(2*6)+(1*7)=82
82 % 10 = 2
So 36002-67-2 is a valid CAS Registry Number.
36002-67-2Relevant articles and documents
Suzuki-Miyaura reactions of the soluble guanylate cyclase inhibitor NS2028: A non-product specific route to C-8 substituted analogues
Berezin, Andrey A.,Koutentis, Panayiotis A.
experimental part, p. 4069 - 4078 (2011/06/24)
Both soluble guanylate cyclase (sGC) inhibitors ODQ 1 and NS2028 2 are synthesized via improved protocols. In the former case treating 3,4-dihydroquinoxalin-2(1H)-one oxime 8, which can be prepared in two steps from 1,2-benzenediamine, with 1,1′-carbonyldiimidazole (CDI) gives the dihydro-ODQ 10 that in the presence of KMnO4 oxidises to give ODQ 1 in an overall yield of 46% starting from 1,2-benzenediamine. In the latter case, the synthesis affords NS2028 2 from 2-amino-4-bromophenol 3 in three steps with an overall yield of 85% and avoids the need for chromatography. Furthermore, Suzuki-Miyaura reaction conditions are described that enable the preparation of 8-aryl and 8-heteroaryl derivatives of NS2028 directly from NS2028 2. Finally, demethylation of the 8-(methoxyphenyl) substituted analogues afforded the 8-(hydroxyphenyl) derivatives 40-42. All new products are fully characterised.
