36004-84-9Relevant academic research and scientific papers
Copper-Catalyzed Hydroxyl-Directed Aminoarylation of Alkynes
Sun, Jiaqiong,Zheng, Guangfan,Xiong, Tao,Zhang, Qiao,Zhao, Jinbo,Li, Yan,Zhang, Qian
, p. 3674 - 3678 (2016)
A facile, copper-catalyzed aminoarylation reaction of various aryl/alkyl alkynes was realized by utilizing N-fluoroarylsulfonimides (NFSI) as aminoarylation or amination reagent with hydroxyl as directing group. With this methodology, various α,β-unsatura
Tandem addition/cyclization for synthesis of 2-aroyl benzofurans and 2-aroyl indoles by carbopalladation of nitriles
Gong, Julin,Hu, Kun,Shao, Yinlin,Li, Renhao,Zhang, Yetong,Hu, Maolin,Chen, Jiuxi
, p. 488 - 494 (2020/02/03)
The first example of the palladium-catalyzed tandem addition/cyclization of 2-(2-acylphenoxy)acetonitriles with arylboronic acids has been developed, providing a new strategy for the synthesis of 2-aroyl benzofurans with excellent chemoselectivity and wid
Microwave Energized Synthesis of 2-Aroylindole Derivatives: Piperidine/DMF as an Effective Medium
Soora Haranath, Jayaprakash,Balam, Satheesh Krishna,Chereddy, Syama Sundar,Sthanikam, Siva Prasad,Sarva, Santhisudha,Gundluru, Mohan,Cirandur, Suresh Reddy
, p. 620 - 625 (2016/04/19)
A convenient and efficient protocol has been developed for the synthesis of 2-aroylindoles (3a, 3b, 3c, 3d, 3e, 3f, 3g, 3h, 3i, 3j) in good yields by the reaction of 2-aminoketones (1a, 1b, 1c) with phenacyl bromides (2a, 2b, 2c, 2d). The reaction success varied with different bases and solvents in both conventional and microwave methods. But finally, it was established that piperidine in DMF was an effective medium to carry out the reaction under microwave irradiation conditions.
Reaction of diphenacylanilines with 2-aminobenzophenone: An abnormal friedlander reaction yielding indoles
Paul, Nidhin,Muthusubramanian, Shanmugam
supporting information, p. 1200 - 1209 (2013/04/10)
This article describes an abnormal Friedlander reaction between diphenacylaniline and 2-aminobenzophenone in the presence of a catalytic amount of (±)-camphorsulfonic acid yielding 2-aroyl-3-arylindoles in quantitative yield. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications to view the free supplemental file.
