3601-88-5 Usage
Type of compound
Organic heterocyclic
Structural components
Pyrimidine ring, piperazine moiety
Pharmaceutical properties
Potential use in drug development
Target disorders
Psychiatric disorders (e.g., depression, anxiety)
Mechanism of action
Serotonin receptor antagonist
Research areas
Neurodegenerative diseases, cancer therapy
Therapeutic potential
Inhibition of DNA synthesis, cell growth
Versatility
Diverse applications in pharmaceuticals and medical research
Check Digit Verification of cas no
The CAS Registry Mumber 3601-88-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,0 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3601-88:
(6*3)+(5*6)+(4*0)+(3*1)+(2*8)+(1*8)=75
75 % 10 = 5
So 3601-88-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H18N4O/c1-20-14-6-3-2-5-13(14)18-9-11-19(12-10-18)15-16-7-4-8-17-15/h2-8H,9-12H2,1H3
3601-88-5Relevant articles and documents
HFIP Promoted Low-Temperature SNAr of Chloroheteroarenes Using Thiols and Amines
Bhujabal, Yuvraj B.,Vadagaonkar, Kamlesh S.,Gholap, Aniket,Sanghvi, Yogesh S.,Dandela, Rambabu,Kapdi, Anant R.
, p. 15343 - 15354 (2019/12/04)
A highly efficient and an unprecedented hexafluoro-2-propanol, promoting low-temperature aromatic nucleophilic substitutions of chloroheteroarenes, has been performed using thiols and (secondary) amines under base-free and metal-free conditions. The developed protocol also provides excellent regio-control for the selective functionalization of dichloroheteroarenes, while the utility of the protocol was demonstrated by the modification of a commercially available drug ceritinib.
