3603-07-4 Usage
Uses
Used in Pharmaceutical Industry:
2-Pyrimidinamine, 5-(2-methoxyethoxy)is used as an intermediate in the synthesis of Glymidine (G752000) for the purpose of predicting human intestinal absorption in drug discovery. 2-Pyrimidinamine, 5-(2-methoxyethoxy)aids in understanding the bioavailability and effectiveness of potential drugs, which is essential for the development of new medications.
Used in Drug Discovery:
2-Pyrimidinamine, 5-(2-methoxyethoxy)is used as a predictive tool for assessing the human intestinal absorption of potential drugs. This application is vital in the early stages of drug development, as it helps researchers determine the feasibility and potential success of a new drug candidate before investing significant resources into further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 3603-07-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,0 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3603-07:
(6*3)+(5*6)+(4*0)+(3*3)+(2*0)+(1*7)=64
64 % 10 = 4
So 3603-07-4 is a valid CAS Registry Number.
3603-07-4Relevant academic research and scientific papers
Mild and highly selective palladium-catalyzed monoarylation of ammonia enabled by the use of bulky biarylphosphine ligands and palladacycle precatalysts
Cheung, Chi Wai,Surry, David S.,Buchwald, Stephen L.
supporting information, p. 3734 - 3737 (2013/08/23)
A method for the Pd-catalyzed arylation of ammonia with a wide range of aryl and heteroaryl halides, including challenging five-membered heterocyclic substrates, is described. Excellent selectivity for monoarylation of ammonia to primary arylamines was achieved under mild conditions or at rt by the use of bulky biarylphosphine ligands (L6, L7, and L4) as well as their corresponding aminobiphenyl palladacycle precatalysts (3a, 3b, and 3c). As this process requires neither the use of a glovebox nor high pressures of ammonia, it should be widely applicable.
