Aldosterone 18-glucuronide is a steroid hormone and the glucuronide conjugate of aldosterone, a hormone produced in the adrenal cortex. It is involved in the regulation of salt and water balance, blood pressure, and electrolyte levels in the body. As a glucuronide conjugate, it is excreted in urine and bile, and its levels can serve as a biomarker for assessing aldosterone metabolism and activity. Alterations in aldosterone 18-glucuronide levels may be associated with conditions such as hypertension, heart failure, and chronic kidney disease, making it an important chemical in the body's hormonal and regulatory systems.
3604-86-2
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Basic information
- Product Name: aldosterone 18-glucuronide
- Synonyms: aldosterone 18-glucuronide
- CAS NO:3604-86-2
- Molecular Formula: C27H36O11
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
- Mol File: 3604-86-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 807.5°Cat760mmHg
- Flash Point: 270°C
- Appearance: /
- Density: 1.51g/cm3
- Vapor Pressure: 3.56E-30mmHg at 25°C
- Refractive Index: 1.64
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: aldosterone 18-glucuronide(CAS DataBase Reference)
- NIST Chemistry Reference: aldosterone 18-glucuronide(3604-86-2)
- EPA Substance Registry System: aldosterone 18-glucuronide(3604-86-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 3604-86-2(Hazardous Substances Data)
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3604-86-2 Usage
Uses
Used in Medical Diagnostics:Aldosterone 18-glucuronide is used as a biomarker for assessing aldosterone metabolism and activity in the body. Its levels can help diagnose and monitor various conditions such as hypertension, heart failure, and chronic kidney disease.
Used in Pharmaceutical Research:
Aldosterone 18-glucuronide is used as a target for the development of drugs that can regulate its levels in the body. This can help manage conditions associated with altered aldosterone metabolism and activity, such as hypertension, heart failure, and chronic kidney disease.
Used in Clinical Trials:
Aldosterone 18-glucuronide is used as a biomarker in clinical trials to evaluate the efficacy of new drugs or treatments targeting aldosterone metabolism and activity. Monitoring its levels can provide valuable insights into the effectiveness of these interventions in managing related health conditions.
Used in Health Monitoring and Management:
Aldosterone 18-glucuronide is used as a parameter for monitoring the health status of individuals, particularly those at risk of or diagnosed with conditions related to aldosterone metabolism and activity. Regular testing of its levels can help in early detection, prevention, and management of these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 3604-86-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,0 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.Calculate Digit Verification of CAS Registry Number 3604-86:
(6*3)+(5*6)+(4*0)+(3*4)+(2*8)+(1*6)=82
82 % 10 = 2
So 3604-86-2 is a valid CAS Registry Number.
InChI:InChI=1/C27H36O11/c1-26-7-6-12(29)8-11(26)2-3-13-14-4-5-15(16(30)10-28)27(14)9-17(18(13)26)36-25(27)38-24-21(33)19(31)20(32)22(37-24)23(34)35/h8,13-15,17-22,24-25,28,31-33H,2-7,9-10H2,1H3,(H,34,35)/t13?,14?,15-,17-,18?,19+,20+,21-,22+,24+,25?,26+,27?/m1/s1
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3604-86-2Downstream Products
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aldosterone 18-glucuronide
