36055-01-3

Upstream product

• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 535-11-5 Ethyl 2-bromopropionate 
• 321125-48-8 1-benzyloxy-2-methoxy-4-[2-nitroprop-1-enyl]benzene 

Downstream Products

• 69986-06-7 1-Benzyloxy-2-methoxy-4-(2-methyl-allyl)-benzene 
• 440367-01-1 [2-(4-Benzyloxy-3-methoxy-phenyl)-1-methyl-ethyl]-((S)-1-phenyl-ethyl)-amine 
• 69986-19-2 N-[2-(4-Benzyloxy-3-methoxy-phenyl)-1,1-dimethyl-ethyl]-propionamide 
• 749797-51-1 [2-(4-Benzyloxy-3-methoxy-phenyl)-1,1-dimethyl-ethyl]-propyl-amine 
• 69986-16-9 2-(4-Benzyloxy-3-methoxy-phenyl)-1,1-dimethyl-ethylamine 
• 69986-20-5 2-Methoxy-4-(2-methyl-2-propylamino-propyl)-phenol 

Relevant academic research and scientific papers

Synthesis and capillary electrophoretic analysis of enantiomerically enriched reference standards of MDMA and its main metabolites

Enantiomerically-enriched (S)-3,4-methylenedioxymethamphetamine (MDMA) and its main metabolites (S)-4-hydroxy-3-methoxymethamphetamine (HMMA) and (S)-3,4-dihydroxymethamphetamine (HHMA) were prepared or unequivocal identification of the differential enantioselective metabolism of these compounds as well as for its application in the analysis of biological samples. Capillary electrophoresis with cyclodextrin derivatives and a chemical correlation of (S)-MDMA, (S)-HMMA and (S)-HHMA has been performed to assign the absolute stereochemistry of major isomers in analytical standards enriched with such enantiomers. Copyright

Process for producing phenylacetones

A phenylacetone or its derivative having the general formula (I): STR1 wherein X, Y, and Z are independently a hydrogen atom, a hydroxyl group, a halogen atom, a nitro group, an amino group, a lower alkyl group having 1 to 6 carbon atoms, a lower alkoxy group having 1 to 6 carbon atoms, or a benzyloxy group and any two substituents of X, Y, and Z may form, together with the benzene ring, a heterocycling ring having 5 to 7 members including 1 or 2 oxygen atoms is produced at a high yield and a high selectivity by reacting a 3-phenylpropylene or its derivative having the general formula (II): STR2 wherein X, Y, and Z are as defined above, with an alkyl nitrite having the general formula (III): wherein R is an aliphatic, aromatic, or alicyclic saturated or unsaturated hydrocarbon group in the presence of (a) water, (b) an alcohol, (c) a palladium catalyst, and (d) an optional amine or copper compound, or by reacting the above-mentioned 3-phenylpropylene or its derivative with the above-mentioned alkyl nitrite in the presence of (a) an alcohol, (b) a palladium catalyst and (c) an optional amine or copper compound to form 1-phenyl-2,2-dialkoxypropane or it derivative having the general formula (IV): STR3 wherein X, Y, Z and R are as defined above, followed by hydrolyzing the reaction product.