360561-80-4Relevant academic research and scientific papers
Total synthesis of (±)-stemonamide and (±)-isostemonamide
Kende, Andrew S,Martin Hernando, Jose I,Milbank, Jared B.J
, p. 61 - 74 (2007/10/03)
Two different approaches to the alkaloids stemonamide and isostemonamide using N-acyliminium chemistry are described. The approach using an aldol spirocyclization to construct the second contiguous spirocenter was successful. The total synthesis of these
First total synthesis of (±)-stemonamide and (±)-isostemonamide
Kende, Andrew S.,Hernando, Jose I. Martin,Milbank, Jared B. J.
, p. 2505 - 2508 (2007/10/03)
(Equation presentation) The total synthesis of the tetracyclic alkaloids stemonamide (1) and isostemonamide (2) is presented. The key step is the reaction between a silyloxyfuran and an N-acyliminium ion. The second quaternary center is created by an intr
