36060-88-5Relevant academic research and scientific papers
Methods for the synthesis of dicarba bridges in organic compounds
-
Page/Page column 36; 115; 125; 126, (2015/11/17)
The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis.
Conotoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides
-
Page/Page column 60-61; 54; 19-20, (2010/11/28)
According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.
