3607-24-7

Basic information

• Product Name: Fenyripol
• Synonyms: α-[(2-Pyrimidinylamino)methyl]benzyl alcohol;1-phenyl-2-(pyrimidin-2-ylamino)ethanol
• CAS NO: 3607-24-7
• Molecular Formula: C12H13N3O
• Molecular Weight: 215.255
• Mol File: 3607-24-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 429.7°Cat760mmHg
• Flash Point: 213.7°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 3.79E-08mmHg at 25°C
• Refractive Index: 1.655
• CAS DataBase Reference: Fenyripol(CAS DataBase Reference)
• NIST Chemistry Reference: Fenyripol(3607-24-7)
• EPA Substance Registry System: Fenyripol(3607-24-7)

Safety Data

• Hazardous Substances Data: 3607-24-7(Hazardous Substances Data)

Usage

Uses

Relaxant.

InChI:InChI=1/C12H13N3O/c16-11(10-5-2-1-3-6-10)9-15-12-13-7-4-8-14-12/h1-8,11,16H,9H2,(H,13,14,15)

Upstream product

• 4595-60-2 2-bromopyrimidine 
• 7568-93-6 2-Amino-1-phenylethanol 

Relevant articles and documents

Engineering N-(2-pyridyl)aminoethyl alcohols as potential precursors of thermolabile protecting groups

Crystal and NMR analyses of four precursors of N-(2-pyridyl) thermolabile protecting group (TPG) were carried out. Two torsion angles have been identified as indicators that predict the molecules' thermolabile properties. Conformation that minimizes the N1...C8 distance is crucial for thermocyclisation. Nucleophilicity of the pyridyl ring is the driving force for the reaction but it is insufficient for thermocyclisation which is dominated by the molecules' ability to adopt a favourable conformation. The pKa value was recorded for all analyzed N-(2-pyridyl)aminoethyl alcohols. However, its effect is small in the determination of thermolability. Based on the analysis that we carried out, N-benzyl N-(2-pyridyl)aminoethyl was selected as a potential precursor of thermolabile carbonate of TPG. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2012.