360795-68-2Relevant academic research and scientific papers
Synthesis of 4-hydroxy-3-quinolinecarboxylic acid derivatives by a condensation/cyclization sequence between o-isocyanobenzoates and magnesium enolates
Kobayashi, Kazuhiro,Nakashima, Toshio,Mano, Masaaki,Morikawa, Osamu,Konishi, Hisatoshi
, p. 602 - 603 (2007/10/03)
Addition of magnesium ester and amide enolates, generated using an excess amount of a magnesium amide (from diisopropylamine and ethylmagnesium bromide), to o-isocyanobenzoates affords 4-hydroxy-3-quinolinecarboxylic esters and amides by a tandem Claisen-type condensation/cyclization sequence.
