36101-54-9Relevant academic research and scientific papers
Direction of bromination and nitration of deoxypeganine and its hydrochloride using HPTLC. Synthesis of 6-bromo(nitro)-, 6,8- dinitrodeoxyvasicinones, 6-nitro(bromo)-, 6,8-dinitrodeoxypeganines, and 6H(bromo)peganols
Shakhidoyatov,Mukarramov,Utaeva
experimental part, p. 625 - 629 (2009/04/07)
The reaction of deoxypeganine (DOP) (1) and its hydrochloride (DOP?HCl) (2) with N-bromosuccinimide and a nitrating mixture was studied. It was found that bromination of DOP occurred at C-4 and the aromatic ring. Nitration of DOP?HCl produced either 6-nitro- or 6,8-dinitro-deoxypeganines and 6-nitrodeoxyvasicinone or their mixture in various ratios depending on the substrate:nitrating mixture ratio. 6Hand 6-Br-deoxypeganines were transformed into the 4-hydroxy derivatives, 6H(Br) peganols or deoxyvasicinones. A method for qualitative and quantitative analysis of the pure compounds and the mixture of reaction products using HPTLC was developed. Springer Science+Business Media, Inc. 2008.
Alkaloids of Nitraria komarovii. Structures of komarin and peganol-N-oxide
Tulyaganov,Makhmudov
, p. 76 - 78 (2007/10/03)
Two alkaloids are isolated from the aerial portions of Nitraria komarovii. Their structures are determined using spectral data and chemical transformations.
ALKALOIDS OF Peganum harmala. UNUSUAL REACTION OF PEGANINE AND VASICINONE
Telezhenetskaya, M. V.,D'yakonov, A. L.
, p. 471 - 474 (2007/10/02)
A number of derivatives of peganine and vasicinone have been obtained: 4-hydroxy-9-O-methylpeganine, isodihydrovasicinone, and 9-methoxy-, 9-phenoxy-, and 9,9-dichlorodeoxyvasicinones.An unusual ease of reduction of vasicinone and of 9-chlorodeoxyvasicinone has been found.An introduction of a hydroxy group into position 4 of a dihydroquinazoline alkaloid with the aid of sodium hydride has been detected.
