36106-47-5

Upstream product

• 87544-95-4 3-carbamoylisonicotinic acid methyl ester hydrochloride 
• 87544-86-3 3-carbamoylisonicotinic acid methyl ester 
• 557-21-1 zinc(II) cyanide 
• 59786-31-1 methyl 3-bromoisonicotinate 

Downstream Products

• 93616-72-9 2-Benzyl-4-(N-benzyl-hydrazino)-2H-pyrido[3,4-d]pyridazin-1-one 
• 87544-87-4 4-aminopyrido<3,4-d>pyridazine-1(2H)-one 
• 1060802-59-6 3-cyanoisonicotinic acid 

Relevant academic research and scientific papers

Spirocyclobutyl Piperidine Derivatives

Disclosed herein is at least one spirocyclobutyl piperidine derivative, at least one pharmaceutical composition comprising at least one spirocyclobutyl piperidine derivative disclosed herein, and at least one method of using at least one spirocyclobutyl piperidine derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.

PYRIDAZINES CONDENSED WITH A HETERO RING, II. PYRIDO AMINOPYRIDAZINES, I. SEPARATION AND STRUCTURE DETERMINATION OF THE ISOMERIC MONOCHLORO COMPOUNDS OBTAINED BY HYDROLYSIS OF 1,4-DICHLOROPYRIDOPYRIDAZINE

The separation of the mixture of isomers 2 and 3, obtained by hydrolysis of 1,4-dichloropyrido pyridazine, was accomplished and the structures of the isomers (2: 1-Cl; 3:4-Cl) were verified by synthesis.Aminolysis of 2 and 3 yielded the hydroxy-ethylamino derivatives 4 and 5; a mixture of these compounds can also be synthesized from 2-tosyloxyethylcinchomeronic imide (20 -> 4, 5) in a good yield (84percent).