361192-69-0

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 361192-58-7 C₄₈H₆₄F₆N₂O₂₃Si 
• 361192-55-4 methyl [2-(trimethylsilyl)ethyl 4,7-di-O-acetyl-9-O-benzyl-3,5-dideoxy-5-trifluoroacetamido-D-glycero-α-D-galacto-non-2-ulopyranosid]onate 
• 361192-52-1 (2R,4S,5R,6R)-4-Acetoxy-6-[(S)-acetoxy-((R)-2-phenyl-[1,3]dioxolan-4-yl)-methyl]-5-(2,2,2-trifluoro-acetylamino)-2-(2-trimethylsilanyl-ethoxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 361192-90-7 methyl [2-(trimethylsilyl)ethyl 8,9-O-benzylidene-3,5-dideoxy-5-trifluoroacetamido-D-glycero-α-D-galacto-non-2-ulopyranosid]onate 
• 361192-46-3 methyl (methyl 4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-5-trifluoroacetamido-D-glycero-β-D-galacto-non-2-ulopyranosid)onate 
• 361192-87-2 methyl [2-(trimethylsilyl)ethyl 3,5-dideoxy-5-trifluoroacetamido-D-glycero-α-D-galacto-non-2-ulopyranosid]onate 
• 108-98-5 thiophenol 
• 361192-67-8 methyl [2,4,7-tri-O-acetyl-9-O-benzyl-3,5-dideoxy-8-O-(methyl 4,7,8,9-tetra-O-acetyl-3,5-dideoxy-5-trifluoroacetamido-D-glycero-α-D-galacto-non-2-ulopyranosylonate)-5-trifluoroacetamido-D-glycero-α-D-galacto-non-2-ulopyranosid]onate 

Relevant academic research and scientific papers

A stereoselective approach for the synthesis of α-sialosides

A highly efficient synthesis of the human melanoma associated antigen GD3 derivative has been described. A key feature of the synthetic approach was the use of sialyl donors that were protected with a C-5 trifiuoroacetamide moiety. These sialyl donors gave high yields and excellent α-anomeric selectivities in direct glycosylations with a wide variety of glycosyl acceptors ranging from C-8 hydroxyls of sialic acids and C-3 hydroxyls of galactosides to reactive primary alcohols.