36136-89-7Relevant academic research and scientific papers
Facile deoxygenation of hydroxylated flavonoids by palladium-catalysed reduction of its triflate derivatives
K?vér, József,Antus, Sándor
, p. 792 - 796 (2005)
An efficient procedure to deoxygenate hydroxy substituted flavonoids, isoflavonoids and related compounds via their trifluoromethanesulfonates is presented. Their reduction with formic acid in the presence of a catalytic amount of palladium acetate, triethylamine and 1,3-bis(diphenyl-phosphanyl) propane (dppp) in DMF results in their des-hyaroxy derivatives without affecting other functional groups.
Oxidative rearrangements of 2'-hydroxychalcones with lh-l-hydroxy-5-methyl- l,2,3-benziodoxathiole 3,3-dioxide
Justik, Michael W.,Zimmerman, Alyssa K.
scheme or table, p. 67 - 71 (2010/03/03)
1H-l-hydroxy-5-methyl-l,2,3-benziodoxathiole 3,3-dioxide (HMBI) has been found to effect the direct conversion of 2'-hydroxychalcones with various B-ring substituents to isoflavones in moderate to good yield (34-83%) in methanol under reflux. The reduced byproduct of HMBI is easily recovered by aqueous extraction and can be recycled and reused with high efficiency. Previous reports of conversions of this type required the use of toxic thallium(III) salts or initial protection of the 2'-hydroxyl group.
