36145-27-4 Usage
General Description
2-CHLORO-N-(6-METHOXYPYRIDIN-3-YL)ACETAMIDE, also known as AMG-232, is a synthetic compound with potential antineoplastic activity. This chemical belongs to the acetamide class and has a molecular weight of 283.71 g/mol. It has been studied for its potential use in cancer treatment, specifically in targeting the p53 pathway, which is often mutated in cancer cells. 2-CHLORO-N-(6-METHOXYPYRIDIN-3-YL)ACETAMIDE has shown promising results in preclinical studies, inhibiting the growth of cancer cells and inducing apoptosis. It may have potential therapeutic applications in the treatment of various types of cancer, although further research and clinical trials are needed to fully assess its safety and efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 36145-27-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,1,4 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 36145-27:
(7*3)+(6*6)+(5*1)+(4*4)+(3*5)+(2*2)+(1*7)=104
104 % 10 = 4
So 36145-27-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H9ClN2O2/c1-13-8-3-2-6(5-10-8)11-7(12)4-9/h2-3,5H,4H2,1H3,(H,11,12)
36145-27-4Relevant articles and documents
Substituted-3H-imidazo[4,5-c]pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) and Stimulator for Interferon Genes (STING) modulators as cancer immunotherapeutics
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Paragraph 0262, (2020/02/19)
Substituted -3H-imidazo[4,5-c]pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) and related compounds, which are useful as inhibitors of ENPP1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the ENPP1.
Fungicidal N-pyridyl haloamides
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, (2008/06/13)
Novel fungicidal pyridyl cyclopropane carboxamides having the general structural formula STR1 wherein R is selected from the group consisting of C1 -C3 alkoxy, C1 -C3 haloalkoxy and halogen; and R1 is C1 -C6 haloalkyl; and fungicidally acceptable organic and inorganic salts thereof.
