361482-95-3

Upstream product

• 361482-84-0 (+)-(2E)-3-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-2-methylbut-2-enoic acid ethyl ester 
• 361482-85-1 (+)-(2Z)-3-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-2-methylbut-2-enoic acid ethyl ester 
• 361482-88-4 (+)-(2E)-3-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-2-methylbut-2-en-1-ol 
• 361482-89-5 (-)-(2Z)-3-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-2-methylbut-2-en-1-ol 
• 361482-92-0 (+)-(4S)-2,2-Dimethyl-4-[(E)-1,2-dimethyl-3-phenylsulfonylprop-1-enyl]-1,3-dioxolane 
• 361482-93-1 (-)-(4S)-2,2-Dimethyl-4-[(Z)-1,2-dimethyl-3-phenylsulfonylprop-1-enyl]-1,3-dioxolane 

Relevant academic research and scientific papers

On The Stereoselectivity the Synthesis of 1-Hydroxymethyl-4-phenylsulfonylbuta-1,3-dienes from β,γ-Unsaturated Sulfones

Starting from D-mannitol, eight β,γ-unsaturated sulfones with different substitution patterns have been synthesised. Reaction of these sulfones with different bases led to 1-hydroxymethyl-4-phenylsulfonylbuta-1,3-dienes with excellent stereocontrol. The stereoselectivity of this reaction is explained and an abbreviated reaction course is proposed that justifies the results obtained.