36151-01-6

Usage

Uses

Used in Pharmaceutical Industry:
7,8-Dihydrovomifoliol is used as a pharmaceutical agent for its anti-inflammatory properties, helping to reduce inflammation in various conditions.
7,8-Dihydrovomifoliol is used as an anti-cancer agent, showing potential in inhibiting the growth of cancer cells and providing a natural alternative for cancer treatment.
Used in Nutraceutical Industry:
7,8-Dihydrovomifoliol is used as a nutraceutical ingredient for its antioxidant properties, protecting against oxidative stress and promoting overall health.
Used in Cosmetic Industry:
7,8-Dihydrovomifoliol is used as an active ingredient in cosmetic products for its anti-inflammatory and skin-soothing effects, beneficial for sensitive and irritated skin conditions.
Used in Research and Development:
7,8-Dihydrovomifoliol is used as a subject of interest in research and development for its potential applications in natural product chemistry and pharmaceutical research, exploring its unique chemical structure and biological activities for new therapeutic opportunities.

Upstream product

• 114226-08-3 (+)-(6S,9R)-9-O-β-D-glucopyranosyloxy-6-hydroxy-3-oxo-α-ionol 

Downstream Products

• 1309362-82-0 (6S,9R)-6,9-dihydroxymegastigman-4-en-3-one 9-(S)-MTPA ester 
• 1309362-81-9 (6S,9R)-6,9-dihydroxymegastigman-4-en-3-one 9-(R)-MTPA ester 

Relevant academic research and scientific papers

Phytochemical and biological studies on rare and endangered plants endemic to China. Part XIV. Structurally diverse terpenoids from the twigs and needles of the endangered plant Picea brachytyla

A phytochemical investigation on the MeOH extract of the twigs and needles of the endangered plant Picea brachytyla led to the isolation and characterization of thirty-eight structurally diverse terpenoids. Seven of these molecules are previously undescribed, including three abietane-type (brachytylins A–C) and one labdane-type (brachytylin D) diterpenoids, an unseparated C-24 epimeric mixture of cycloartane-type triterpenoids (brachytylins E/F, ratio: 1:1), and a rare rearranged 12(1 → 6)-abeo-megastigmane glycoside (brachytylins G). Their structures and absolute configurations were determined by extensive spectroscopic (e.g., detailed 2D NMR and ECD) methods and/or X-ray diffraction analyses. All the isolates were evaluated for their inhibitory activities against the adenosine triphosphate (ATP)-citrate lyase (ACL) and the Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2). Among them, abiesadine J showed inhibitory effect against ACL, displaying an IC50 value of 17 μM. 3S,23R-Dihydroxycycloart-24-en-26-oic acid exhibited inhibitory effect on SHP2, with an IC50 value of 19 μM. Meanwhile, 3R*,23S*-dihydroxycycloart-24-en-26-oic acid was found to have inhibitory effects against both ACL and SHP2, with IC50 values of 16 and 12 μM, respectively.

Reinvestigation of the absolute stereochemistry of megastigmane glucoside, icariside B5

Icariside B5 is one of the widely distributed megastigmane glucosides among plant sources. The absolute structure of icariside B 5 was reinvestigated by chemical conversion from the related compound and the application of the modifie