36177-79-4 Usage
General Description
1-(Chloromethyl)-3,4-dihydroisoquinoline is a chemical compound with the molecular formula C10H11ClN. It is a member of the isoquinoline family, which is a class of organic compounds containing a benzene ring fused to a pyridine ring. The presence of a chloromethyl group in the compound makes it a chlorinated derivative of 3,4-dihydroisoquinoline. 1-(CHLOROMETHYL)-3,4-DIHYDROISOQUINOLINE has potential applications in medicinal chemistry, particularly in the development of pharmaceutical drugs. Its structure and reactivity make it a useful building block for the synthesis of various biologically active molecules. Additionally, it may have potential applications in agrochemical and material science industries. However, it is important to handle this compound with care, as chlorinated compounds can be toxic and/or hazardous to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 36177-79-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,1,7 and 7 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 36177-79:
(7*3)+(6*6)+(5*1)+(4*7)+(3*7)+(2*7)+(1*9)=134
134 % 10 = 4
So 36177-79-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H10ClN/c11-7-10-9-4-2-1-3-8(9)5-6-12-10/h1-4H,5-7H2
36177-79-4Relevant articles and documents
1,4-Dehydrochlorination of 1-(1-haloalkyl)-3,4-dihydroisoquinolines as a convenient route to functionalized isoquinolines
Jacobs, Jan,Van, Tuyen Nguyen,Stevens, Christian V.,Markusse, Peter,De Cooman, Paul,Maat, Leendert,De Kimpe, Norbert
scheme or table, p. 3698 - 3701 (2009/10/11)
1-Chloroalkyl-, 1-(2,2-dichloroalkyl)-, and 1-(trichloromethyl)-3,4-dihydroisoquinolines are synthesized by chlorination of 1-alkyl-3,4-dihydroisoquinolines with N-chlorosuccinimide. These novel chlorinated 3,4-dihydroisoquinolines are suitable precursors for functionalized isoquinolines by aromatization involving sequential 1,4-dehydrochlorination, tautomerization, and nucleophilic substitution.
