36193-84-7Relevant academic research and scientific papers
An efficient and convenient palladium catalyst system for the synthesis of amines from allylic alcohols
Banerjee, Debasis,Jagadeesh, Rajenahally V.,Junge, Kathrin,Junge, Henrik,Beller, Matthias
, p. 2039 - 2044 (2013/01/15)
A novel catalyst system for efficient amination of allylic alcohols with aryl and alkyl amines is presented. By applying a convenient combination consisting of Pd(OAc)2/1,10-phenanthroline, a variety of allylic alcohols reacted smoothly to give the corresponding secondary and tertiary amines in good to excellent yields with high regioselectivity. The usefulness of our protocol is demonstrated in the one-step synthesis of the antifungal drug naftifine and the calcium channel blocker flunarizine. One pot is all it takes: By applying a convenient combination consisting of Pd(OAc)2/1,10- phenanthroline, a variety of allylic alcohols reacts smoothly to give the corresponding secondary and tertiary amines in good to excellent yields with high regioselectivity (see picture).
Highly efficient and regioselective allylation with allylic alcohols catalyzed by [Mo3S4Pd(η3-allyl)] clusters
Tao, Yinsong,Wang, Bo,Wang, Baomin,Qu, Lihong,Qu, Jingping
experimental part, p. 2726 - 2729 (2010/08/06)
(Figure presented) A highly efficient and regioselective allylation reaction of amines and active methylene compounds directly using allylic alcohols under mild conditions catalyzed by the novel cubane-type sulfido [(CpMo)3(μ3-S)4Pd(η3-allyl)] [PF6]2 clusters has been developed. A variety of allylic alcohols and nucleophiles including amines and active methylene compounds are investigated, and in the case of allylic alcohols bearing substituents at either the α- or γ-position only linear products are obtained.
Highly efficient and regioselective allylic amination of allylic alcohols catalyzed by [Mo3PdS4] cluster
Tao, Yinsong,Zhou, Yuhan,Qu, Jingping,Hidai, Masanobu
experimental part, p. 1982 - 1984 (2010/06/21)
A highly efficient and regioselective allylation reaction of amines with allylic alcohols under mild conditions catalyzed by the cubane-type sulfido cluster [(Cp*Mo)3S4Pd(dba)][PF6] with H3BO3 as an additive has been developed. A variety of amines and allylic alcohols are investigated, and in the case of allylic alcohols bearing substituents at either α- or γ-position only linear allylic amination products are obtained.
Synthesis and Reactions of Allylic and Homoallylic Pyrophosphate Tetraesters
Butsugan, Yasuo,Nagai, Kenji,Nagaya, Fumitoshi,Tabuchi, Hiroki,Yamada, Katsuhisa,Araki, Shuki
, p. 1707 - 1714 (2007/10/02)
Pyrophosphate tetraesters possessing allylic and homoallylic side chains were synthesized.Reaction of alkyl allyl (and 3-methyl-3-butenyl) phosphorochloridates with sodium hydrogencarbonate gave P1,P2-dialkyl P1,P2-diallyl and P1,P2-bis(3-methyl-3-buteny
