361979-01-3

Upstream product

• 17430-98-7 [(1S)-1-cyclohexylethyl]amine 
• 583-53-9 2,3-dibromobenzene 

Downstream Products

• 407618-16-0 N-[(S)-1-cyclohexylethyl]-N'-(diphenylmethylene)-1,2-benzenediamine 
• 407618-22-8 N-[(S)-1-cyclohexylethyl]-1,2-benzenediamine 
• 407618-37-5 1-[(S)-1-cyclohexylethyl]-1H-benzimidazole 
• 361979-03-5 N-phenyl-N'-(S)-1-cyclohexylethyl-1,2-diaminobenzene 

Relevant academic research and scientific papers

Synthesis of new benzimidazolium salts and their application in the asymmetric arylation of aldehydes

A series of novel chiral benzimidazolium salts, the precursor of N-heterocyclic carbene ligands, were designed and synthesized from 1,2-dibromobenzene. In situ prepared corresponding carbenes were tested in asymmetric Rh-catalyzed arylation of aromatic aldehydes, affording chiral diarylmethanols with high yields and moderate enantioselectivities.

A versatile synthesis of substituted benzimidazolium salts by an amination/ ring closure sequence

(Equation presented) A new method to produce benzimidazolium salts based on a successive Buchwald-Hartwig amination and ring closure is reported. A variety of different benzimidazolium salts can be prepared using this procedure. Amines that bear an α-chir