362050-99-5Relevant academic research and scientific papers
Synthesis and biological evaluation of new 1,5-diazaanthraquinones with cytotoxic activity
Manzanaro, Sonia,Vicent, María Jesús,Martín, María Jesús,Salvador-Tormo, Nélida,Pérez, José María,Del Mar Blanco, María,Avenda?o, Carmen,Menéndez, José Carlos,De La Fuente, Jesús ángel
, p. 6505 - 6515 (2007/10/03)
A series of 1,5-diazaanthraquinone derivatives was synthesized and their in vitro cytotoxic activities were evaluated against several human cancer cell lines. The 1,5-diazaanthraquinone chromophore has been synthesized either on the basis of hetero Diels-
A C-ring regioisomer of the marine alkaloid meridine exhibits selective in vitro cytotoxicity for solid tumours
ángel de la Fuente, Jesús,Jesús Martín, Ma,Del Mar Blanco, Ma,Pascual-Alfonso, Eva,Avendao, Carmen,Carlos Menéndez
, p. 1807 - 1814 (2007/10/03)
9-Hydroxybenzo[b]pyrido[4,3,2-de](1,10)-phenantrolin-8-one (1) a regioisomer of the marine alkaloid meridine, was synthesized from 5,8-dimethoxy-6-nitro-4(1H)-quinolinone in eight steps and 23% overall yield. A shorter route was also investigated, based o
