36234-66-9Relevant academic research and scientific papers
COMPOUNDS AND METHODS FOR TREATING CANCER
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, (2018/05/24)
Substituted hydrazone compounds, methods of making such compounds and metal complexes thereof, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds and metal complexes to treat, prevent or ameliorate cancer are provided.
3-Bromocyclohexane-1,2-dione as a useful reagent for Hantzsch synthesis of thiazoles and the synthesis of related heterocycles
Guernon, Jason M.,Wu, Yong-Jin
, p. 3633 - 3635 (2011/07/29)
We describe the use of 3-bromocyclohexane-1,2-dione, an air stable, versatile reagent for the Hantzsch thiazole synthesis and the synthesis of other closely related heterocycles.
Azole derivatives as histamine H3 receptor antagonists, Part I: Thiazol-2-yl ethers
Walter,Von Coburg,Isensee,Sander,Ligneau,Camelin,Schwartz,Stark
supporting information; experimental part, p. 5879 - 5882 (2010/11/18)
Most human histamine H3 receptor (hH3R) antagonists follow a general structural blueprint, containing a basic moiety linked by a spacer to a substituted core element. In this investigation the acceptance of thiazol-2-yl ether moieties in the core region is proved with some ether derivatives showing hH3R binding affinities in the nanomolar concentration range. A diversity of structural motifs is used as substituents to enhance the in vitro hH3R binding affinity.
