362521-36-6 Usage
General Description
1,3,4-Thiadiazole-2-sulfonyl chloride is a chemical compound with the molecular formula C2H2ClN3O2S. It is a white to off-white crystalline powder with a melting point of 104-106°C. 1,3,4-THIADIAZOLE-2-SULFONYL CHLORIDE is primarily used in organic synthesis as a reagent in the preparation of various pharmaceutical and agrochemical intermediates. It is a versatile building block in the production of diverse heterocyclic compounds and has potential applications in the development of new drug molecules. Additionally, it can also be used in the fields of material science and biochemistry. Thiadiazole-2-sulfonyl chloride is a valuable tool in the production of specialized chemicals for various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 362521-36-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,2,5,2 and 1 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 362521-36:
(8*3)+(7*6)+(6*2)+(5*5)+(4*2)+(3*1)+(2*3)+(1*6)=126
126 % 10 = 6
So 362521-36-6 is a valid CAS Registry Number.
InChI:InChI=1/C2HClN2O2S2/c3-9(6,7)2-5-4-1-8-2/h1H
362521-36-6Relevant articles and documents
Synthesis of certain diarylsulfonylureas as antitumor agents
Youssef,Al-Abdullah,El-Khamees
, p. 404 - 418 (2007/10/03)
A new series of N-aryl-N′-heteroaryl or N,N′-diheteroaryl sulfonylurea or sulfonylthiourea was synthesized and screened for their antitumor activity at the National Cancer Institute (NCI). N-(3-Chlorophenyl)-N′-(6-methyl-uracil-2-sulfonyl)urea (28) with GI50, TGI, LC50 (MG-MID) values of 66.1, 83.2, 93.3 μM, respectively is the most active compound in this study. It showed a remarkable activity more than sulofenur against HL-60 (TB) and RPMI-8226 leukemia, HOP-92 Non small lung cancer, KM12 colon cancer, SF-295 CNS cancer, PC-3 prostate cancer, OVCAR-4 Ovarian cancer, CAKI-1 and UO-31 Renal cancer, and MDA-MB-435 Breast cancer with GI50 values of 0.3, 2.7, 6.9, 14.7, 8.2, 9.3, 2.0, 2.1, 3.4, 11.3 μM, respectively.
C:Corrosive;
