362595-93-5

Upstream product

• 1122-62-9 2-acetylpyridine 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 28611-39-4 4-(dimethylamino)benzene-boronic acid 
• 134653-69-3 4'-{[(Trifluoromethyl)sulfonyl]oxy}-2,2':6',2''-terpyridine 

Downstream Products

• 405149-92-0 Os(CH₃)2N(C₆H₄C₅H₂N(C₅H₄N)2)Cl₃ 
• 405149-91-9 Ru(III)[4'-(4-dimethylaminophenyl)-2,2': 6',2''-terpyridine]Cl₃ 
• 1207181-54-1 C₂₃H₂₀Cl₂N₄Zn 

Relevant academic research and scientific papers

Selective detection of pyrophosphate anion by a simple Cd(II) based terpyridine complex

A simple ratiometric terpyridine-Cd(ll) complex was synthesized by the treatment of CdCl2 with terpyridine ligand 4′-(4-N,N′-dimethylaminophenyl)-2,2′:6′,2″-terpyridine. The synthesized complex was found to act as a selective fluorescent chemosensor for pyrophosphate P2O74?? (PPi) over other anions like F?, Cl?, Br?, CO32??, SO32??, AcO?, NO2?, and H2PO4?. Furthermore, the receptor probe was also successfully employed in HeLa cell for PPi detection, which indicates this can be used as a chemosensor for cells.

A new, highly fluorescent terpyridine which responds to zinc ions with a large red-shift in emission

A sequence of three metal-catalysed aryl coupling reactions leads to the new ligand 4′-(4-N,N-diphenylaminophenyl)2,2′:6′,2″-terpyridine, the intense ICT emission of which undergoes a large red-shift upon binding of zinc ions, providing a unique response over other common metal ions.

Optical Response of Terpyridine Ligands to Zinc Binding: A Close Look at the Substitution Effect by Spectroscopic Studies at Low Temperature

Terpyridine (tpy) ligands are popular building blocks to bind metal ions. Several tpy ligands with different substituents were synthesized and examined for their binding with zinc cation. The study revealed a large substituent effect on the zinc binding-i

Structure-dependent and environment-responsive optical properties of the trisheterocyclic systems with electron donating amino groups

A series of 2,2′:6′,2″-terpyridine (terpy), 2,6-di(thiazol-2-yl)pyridine (dtpy), and 2,6-di(pyrazin-2-yl)pyridine (dppy) derivatives with electron donating amino groups (dimethylamine, piperidine, morpholine and diphenylamine) connected to the terpy/dtpy/

Highly Efficient Ir(III)-Coumarin Photo-Redox Catalyst for Synergetic Multi-Mode Cancer Photo-Therapy

Four photo-catalysts of the general formula [Ir(CO6/ppy)2(L)]Cl where CO6=coumarin 6 (Ir1–Ir3), ppy=2-phenylpyridine (Ir4), L=4′-(3,5-di-tert-butylphenyl)-2,2′ : 6′,2′′-terpyridine (Ir1), 4′-(3,5-bis(trifluoromethyl)phenyl)-2,2′ : 6′,2′′-terpyr

Living Long and Prosperous: Productive Intraligand Charge-Transfer States from a Rhenium(I) Terpyridine Photosensitizer with Enhanced Light Absorption

The ground- and excited-state properties of six rhenium(I) κ2N-tricarbonyl complexes with 4′-(4-substituted-phenyl)terpyridine ligands bearing substituents of different electron-donating abilities were evaluated. Significant modulation of the electrochemical potentials and a nearly 4-fold variation of the triplet metal-to-ligand charge-transfer (3MLCT) lifetimes were observed upon going from CN to OMe. With the more electron-donating NMe2group, we observed in the κ2N complex the appearance of a very strong absorption band, red-shifted by ca. 100 nm with respect to the other complexes. This was accompanied by a dramatic enhancement of the excited-state lifetime (380 vs 1.5 ns), and a character change from 3MLCT to intraligand charge transfer (3ILCT), despite the remote location of the substituent. The dynamics and character of the excited states of all complexes were assigned by combining transient IR spectroscopy, IR spectroelectrochemistry, and (time-dependent) density functional theory calculations. Selected complexes were evaluated as photosensitizers for hydrogen production, with the κ2N-NMe2complex resulting in a stable and efficient photocatalytic system reaching TONRevalues of over 2100, representing the first application of the 3ILCT state of a rhenium(I) carbonyl complex in a stable photocatalytic system.

Coordination Environment Prevents Access to Intraligand Charge-Transfer States through Remote Substitution in Rhenium(I) Terpyridinedicarbonyl Complexes

Six rhenium(I) κ3N-dicarbonyl complexes with 4′-(4-substituted phenyl)terpyridine ligands were evaluated in their ground and excited states. These complexes, bearing substituents of different electron-donating strengths - from CN to NMe2 - were studied by a combination of transient IR (TRIR), electrochemistry, and IR spectroelectrochemistry, as well as time-dependent density functional theory (TD-DFT). They exhibit panchromatic absorption and can act as stronger photoreductants than their tricarbonyl counterparts. The ground- and excited-state potentials, absorption maxima, and lifetimes (250-750 ps) of these complexes correlate well with the Hammett σp substituent constants, showing the systematic effect of remote substitution in the ligand framework. TRIR spectroscopy allowed us to assign the lowest singlet and triplet excited states to a metal-to-ligand charge-transfer (MLCT) character. This result contrasts our previous report on analogous κ2N-tricarbonyl complexes, where remote substitution switched the character from MLCT to intraligand charge transfer. With the help of TD-DFT calculations, we dissect the geometric and electronic effects of coordination of the third pyridine, local symmetries, and increasing conjugation length. These results give valuable insights for the design of complexes with long-lived triplet excited states and enhanced absorption throughout the visible spectrum, while showcasing the boundaries of the excited-state switching strategy via remote substitution.

Synthesis, characterization and photovoltaic studies of 2,2′;6′,2?-terpyridine-based ruthenium complexes with phenylamino, anthranyl and furfuryl substitutions at the 4′-position

A series of two heteroleptic ruthenium complexes of the type [Ru(X-tpy)(bpy-COOH)(NCS)](PF6) (where X-tpy = 4′-(4-N,N-dimethylaminophenyl)-2,2′:6′,2?-terpyridine for complex 1 and 4′-(9-anthryl)-2,2′:6′,2?-terpyridine for complex 2, bpy-COOH = 4,4′-dicarboxy-2,2′-bipyridine) and another heteroleptic ruthenium complex of the type [Ru(X-tpy)(bpy-COOH)(NCS)]Cl (where X-tpy = 4′-(furan-2-yl)-2,2′:6′,2?-terpyridine for complex 3, bpy-COOH = 4,4′-dicarboxy-2,2′-bipyridine) have been synthesized and fully characterized. The effects of these substitutions with varying electronic properties on the resulting ruthenium dyes were studied in relation to their electronic structure and consequent redox chemistry and photovoltaic performance in a DSSC setup. Complex 1 registers a better photovoltaic performance with photon to conversion efficiency (PCE) of (η = 1.41%) with a J sc value of 2.1 mA cm?2 and V oc 0.58 V followed by 2 (η = 0.44%) and 3 (η = 0.13%). The pattern for the photovoltaic performance has been justified with a theoretical analysis of the directionality of the most intense charge transfers taking place in the dyes upon light irradiation.

Novel mitochondrion-targeting iridium complex as well as preparation method and application thereof

The invention discloses a novel mitochondrion-targeting iridium complex. The chemical structural formula of the iridium complex is shown as a formula (I), and the iridium complex is abbreviated as IrCo6-tpy. The iridium complex IrCo6-tpy has cytotoxicity to cancer cells of different tissue parts of a human body, and has stronger anti-hepatoma cell activity compared with an anti-tumor complex cis-platinum (Pt(NH3)2Cl2); moreover, the iridium complex IrCo6-tpy has a mitochondrial targeting function, can be used as a novel antitumor drug taking tumor cell mitochondria as a target, is beneficial to development of an efficient anticancer preparation, and has a relatively great application prospect.

A terpyridine zinc complex for selective detection of lipid pyrophosphates: A model system for monitoring bacterial O- And N-transglycosylations

To develop an effective method for probing O- and Nglycosyltransfer reactions that are accompanied by the release of undecaprenyl pyrophosphate, solanesyl pyrophosphate (SPP) is used as a surrogate to bind a terpyridine zinc complex (Tpy-Zn), forming a fluorescent [Tpy-Zn]-SPP complex (Kass 106,000 M-1 in EtOH-CHCl3) with 5.8 μM LOD in HEPES buffer (10 mM, pH 7.4) containing 10 mM CaCl2 and 0.08% decyl PEG, which is similar to the bioassay conditions for lipid II polymerization.