362601-84-1

Basic information

• Product Name: Benzene, 2-chloro-4-fluoro-1-isothiocyanato- (9CI)
• Synonyms: Benzene, 2-chloro-4-fluoro-1-isothiocyanato- (9CI)
• CAS NO: 362601-84-1
• Molecular Formula: C₇H₃ClFNS
• Molecular Weight: 187.6218232
• Product Categories: ISOTHIOCYANATE
• Mol File: 362601-84-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzene, 2-chloro-4-fluoro-1-isothiocyanato- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2-chloro-4-fluoro-1-isothiocyanato- (9CI)(362601-84-1)
• EPA Substance Registry System: Benzene, 2-chloro-4-fluoro-1-isothiocyanato- (9CI)(362601-84-1)

Safety Data

• Hazardous Substances Data: 362601-84-1(Hazardous Substances Data)

Upstream product

• 463-71-8 thiophosgene 
• 2106-02-7 2-chloro-4-fluoroaniline 
• 1544-68-9 4-fluorophenyl isothiocyanate 

Relevant articles and documents

2-AMINOQUINAZOLINONE DERIVATIVE

The present invention provides a 2-aminoquinazolinone derivative. The present invention is a compound represented by formula (1) [wherein X1 represents CR or N, X2 represents CR2 or N, X3 represents CR3 or N, Y represents an optionally substituted C6-10 aryl or optionally substituted 6 to 10-membered heteroaryl, Z represents an optionally substituted C6-10 aryl, RA represents a hydrogen atom, halogen, cyano, optionally substituted C1-6 alkyl sulfonyl, optionally substituted C1-6 alkyl, or optionally substituted C1-6 alkoxy, and R1, R2, and R3 independently represent a hydrogen atom, halogen, optionally substituted C1-6 alkyl, or optionally substituted C1-6 alkoxy] or a pharmaceutically acceptable salt thereof.

Tricyclic Compounds As mPGES-1 Inhibitors

The present invention relates to tricyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.