362660-19-3

Upstream product

• 917-54-4 methyllithium 
• 134107-65-6 (3R,7aS)-3-phenyl-3,7a-dihydro-1H-pyrrolo[1,2-c]oxazol-5-one 
• 103201-79-2 (3R,7aS)-3-phenyl-tetrahydro-pyrrolo[1,2-c]oxazol-5-one 

Downstream Products

• 771578-93-9 (2S,3S)-3-methyl-5-oxopyrrolidine-2-carboxylic benzoic anhydride 
• 362660-21-7 (2R,5S,6S,7R)-6,7-dimethyl-2-phenyl-1-aza-3-oxabicyclo[3.3.0]octan-8-one 
• 362660-27-3 (3S,4R)-3,4-dimethyl-(S)-pyroglutamic acid 
• 771578-92-8 (2S,3S)-2-(N-tert-butoxycarbonyl-N-methylamino)-5-(tert-butyldimethylsiloxy)-3-methylpentanoic acid benzyl ester 
• 771578-98-4 (2S,3S)-2-tert-butoxycarbonylamino-5-(tert-butyldimethylsiloxy)-3-methylpentanoic acid benzyl ester 
• 771578-96-2 (2S,3S)-2-tert-butoxycarbonylamino-3-methyl-1,5-pentanedioic acid 1-benzyl ester 
• 771578-97-3 (2S,3S)-2-tert-butoxycarbonylamino-5-hydroxy-3-methylpentanoic acid benzyl ester 
• 771578-95-1 (2S,3S)-3-methyl-5-oxopyrrolidine-1,2-dicarboxylic acid 2-benzyl ester 1-tert-butyl ester 
• 771578-94-0 (2S,3S)-3-methyl-5-oxopyrrolidine-2-carboxylic acid benzyl ester 
• 362660-20-6 (2R,5S,6S,7S)-6,7-dimethyl-2-phenyl-1-aza-3-oxabicyclo[3.3.0]octan-8-one 

Relevant academic research and scientific papers

Stereoselective synthesis of (3S,4R)-3,4-dimethyl-(S)-glutamine and the absolute stereochemistry of the natural product from papuamides and callipeltin

(3S,4R)-3,4-Dimethyl-(S)-glutamine, a common component of cyclodepsipeptides, papuamide A and callipeltin A, was stereoselectively prepared from (S)-pyroglutamic acid. The stereostructure of natural dimethylglutamine was unambiguously confirmed to be (2S,

Stereoselective synthesis of protected (2S,3S)-N-methyl-5- hydroxyisoleucine, a component of halipeptins

The stereocontrolled synthesis of the protected (2S,3S)-N-methyl-5- hydroxyisoleucine, a component of halipeptins A and B with potent anti-inflammatory activity, has been achieved. The key steps include (i) installation of a double bond to bicyclic lactam