362705-08-6Relevant articles and documents
Synthetic study of polyoxypeptin: Stereoselective synthesis of (2S,3R)-3-hydroxy-3-methylproline
Noguchi, Yasuo,Uchiro, Hiromi,Yamada, Tatsuhiro,Kobayashi, Susumu
, p. 5253 - 5256 (2001)
The first synthesis of (2S,3R)-3-hydroxy-3-methylproline, which is a novel amino acid of polyoxypeptin, a potent inducer of apoptosis in human pancreatic carcinoma AsPC-1, was accomplished. The key feature of the synthesis is the palladium-catalyzed intra