1-(prop-2-ynyl)-1,2-dihydropyridin-2-one is an organic compound with the molecular formula C8H7NO2. It is a derivative of dihydropyridin-2-one, featuring a prop-2-ynyl group attached to the first carbon atom. 1-(prop-2-ynyl)-1,2-dihydropyridin-2-one is known for its potential applications in various fields due to its unique chemical structure and properties.
36281-70-6
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Basic information
- Product Name: 1-(prop-2-ynyl)-1,2-dihydropyridin-2-one
- Synonyms: 1-(prop-2-ynyl)-1,2-dihydropyridin-2-one
- CAS NO:36281-70-6
- Molecular Formula:
- Molecular Weight: 133.15
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1-(prop-2-ynyl)-1,2-dihydropyridin-2-one(CAS DataBase Reference)
- NIST Chemistry Reference: 1-(prop-2-ynyl)-1,2-dihydropyridin-2-one(36281-70-6)
- EPA Substance Registry System: 1-(prop-2-ynyl)-1,2-dihydropyridin-2-one(36281-70-6)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 36281-70-6(Hazardous Substances Data)
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36281-70-6 Usage
Uses
1. Used in Pharmaceutical Industry:1-(prop-2-ynyl)-1,2-dihydropyridin-2-one is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
2. Used in Synthesis of Camptothecin Analogs:
1-(prop-2-ynyl)-1,2-dihydropyridin-2-one is used as a building block in the synthesis of the ABCD ring cores of camptothecin, a potent anticancer drug. Camptothecin and its analogs are known for their ability to inhibit topoisomerase I, a crucial enzyme in DNA replication, thereby exhibiting significant antitumor activity.
3. Used in Drug Delivery Systems:
Similar to gallotannin, 1-(prop-2-ynyl)-1,2-dihydropyridin-2-one can be incorporated into drug delivery systems to enhance its bioavailability and therapeutic efficacy. By utilizing advanced drug delivery technologies, such as nanoparticles and liposomes, the compound can be more effectively targeted to specific cells or tissues, improving its overall performance in treating various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 36281-70-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,2,8 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.Calculate Digit Verification of CAS Registry Number 36281-70:
(7*3)+(6*6)+(5*2)+(4*8)+(3*1)+(2*7)+(1*0)=116
116 % 10 = 6
So 36281-70-6 is a valid CAS Registry Number.
36281-70-6Upstream product
36281-70-6Downstream Products
- 864950-94-7 1-[3-(2-phenylethynyl-phenyl)-prop-2-ynyl]-1H-pyridin-2-one
- 1063631-42-4 trans-Pt(PPh3)2(N-propargyl-2-pyridone(-H))2
- 1616268-18-8 (1S,2S)-dibenzyl 2-benzyloxy-1-hydroxy-3-{4-[(2-oxopyridin-1-yl)methyl]-1H-1,2,3-triazol-1-yl}propylphosphonate
- 1616268-32-6 (1R,2S)-dibenzyl 2-benzyloxy-1-hydroxy-3-{4-[(2-oxopyridin-1-yl)methyl]-1H-1,2,3-triazol-1-yl}propylphosphonate
- 1400816-32-1 1-(3-phenylprop-2-yn-1-yl)pyridin-2(1H)-one
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1-(prop-2-ynyl)-1,2-dihydropyridin-2-one
