36304-97-9Relevant academic research and scientific papers
Anti-platelet aggregation activity of some pyrazines
Ohta, Akihiro,Takahashi, Hiromitsu,Miyata, Naoomi,Hirono, Hiroyuki,Nishio, Toyotaka,Uchino, Etsuo,Yamada, Kenji,Aoyagi, Yutaka,Suwabe, Yasushi,Fujitake, Masayuki,Suzuki, Takahiro,Okamoto, Kazuo
, p. 1076 - 1081 (2007/10/03)
This report describes the anti-platelet aggregation activity of 48 pyrazines. Among alkyl- and arylpyrazines tested, 2,3-diphenylpyrazines showed the strongest anti-platelet aggregation activity. Then, various substituents were introduced into the phenyl groups, and the 2,3-bis(p- methoxyphenyl)pyrazine derivatives were consequently found to possess considerably strong inhibitory activity.
