36324-58-0Relevant academic research and scientific papers
Enantioselective Synthesis of Cα-Tetrasubstituted N-Hydroxyl-α-amino Nitriles via Cyanation of Ketonitrones Using Me2(CH2Cl)SiCN
Xu, Peng-Wei,Cui, Xiao-Yuan,Chen, Chen,Zhou, Feng,Yu, Jin-Sheng,Ao, Yu-Fei,Zhou, Jian
supporting information, p. 8471 - 8476 (2021/11/01)
Here, we report an unprecedented catalytic enantioselective cyanation of ketonitrones enabled by the bifunctional cyanating reagent Me2(CH2Cl)SiCN. This approach allows facile access to optically active N-hydroxyl-α-amino nitriles that are of high synthet
Metal-free C(sp3)-H bond sulfonyloxylation of 2-alkylpyridines and alkylnitrones
Wang, Chang-Sheng,Dixneuf, Pierre H.,Soulé, Jean-Fran?ois
supporting information, p. 4954 - 4957 (2018/07/25)
Pyridin-2-ylmethyl tosylate derivatives are obtained in high yields from 2-alkylpyridine 1-oxides via a [3,3]-sigmatropic rearrangement of the adduct between 2-alkylpridine 1-oxides with benzenesulfonyl chlorides. Moreover, alkylnitrones also undergo [3,3]-sigmatropic rearrangement to give α-tosylated ketones after hydrolysis. Substitution reactions with nucleophiles then lead to diverse useful functionalizations for the synthesis of pincer ligands.
One-Pot Sequential [3 + 3] Dipolar Cycloaddition of Aldehyde or Ketone and Hydroxylamine with Spirocyclopropyl Oxindole
Xu, Peng-Wei,Chen, Chen,Liu, Jia-Kuan,Song, Yu-Ting,Zhou, Feng,Yan, Jun,Zhou, Jian
, p. 12763 - 12774 (2018/10/20)
A Sc(OTf)3-catalyzed highly diastereoselective one-pot sequential [3 + 3] dipolar cycloaddition reaction of aldehyde or ketone, N-alkyl hydroxylamine, and spirocyclopropyl oxindole is developed, allowing facile construction of spirocyclic oxind
A Multiheteroatom [3,3]-Sigmatropic Rearrangement: Disproportionative Entries into 2-(N-Heteroaryl)methyl Phosphates and α-Keto Phosphates
Yang, Yongkang,Qu, Chen,Chen, Xiaolan,Sun, Kai,Qu, Lingbo,Bi, Wenzhu,Hu, Hao,Li, Rui,Jing, Chunfeng,Wei, Donghui,Wei, Shengkai,Sun, Yuanqiang,Liu, Hui,Zhao, Yufen
supporting information, p. 5864 - 5867 (2017/11/10)
A novel multiheteroatom (N, O and P) [3,3]-sigmatropic rearrangement is disclosed, based on two important types of organophosphates, 2-(N-heteroaryl) methyl phosphates and α-keto phosphates, being accessed smoothly and efficiently.
