363607-10-7Relevant articles and documents
The rational design of inhibitors of nitric oxide formation by inducible nitric oxide synthase
Whitlow, Marc,Adler, Marc,Davey, David,Huang, Qinglan,Koovakkat, Sunil,Parkinson, John F.,Pham, Eric,Polokoff, Mark,Xu, Wei,Yuan, Shendong,Phillips, Gary
, p. 2505 - 2508 (2007)
A series of compounds was rationally designed as inhibitors of dimer formation of the inducible isoform of nitric oxide synthase, and subsequent nitric oxide production. The conformation of two fragments obtained from a crystal structure was utilized to d