363609-35-2Relevant academic research and scientific papers
Synthesis of optically active aldol derivatives through chirality transfer type 1,2-Wittig rearrangement of α-alkoxycarboxamides
Kitagawa, Osamu,Momose, Shu-Ichi,Yamada, Yoichiro,Shiro, Motoo,Taguchi, Takeo
, p. 4865 - 4868 (2007/10/03)
Treatment of chiral α-benzyloxy- or α-propargyloxycarboxamide with tert-BuLi gave β-hydroxycarboxamides (aldol derivatives) in high optical purity through the formation of α-lithiated ethers and the subsquent 1,2-Wittig rearrangement.
