36402-53-6

Basic information

• Product Name: 2,4-Hexanediol, 5-methyl-, (2R,4R)-rel-
• CAS NO: 36402-53-6
• Molecular Formula: C7H16O2
• Molecular Weight: 132.203
• Mol File: 36402-53-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,4-Hexanediol, 5-methyl-, (2R,4R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Hexanediol, 5-methyl-, (2R,4R)-rel-(36402-53-6)
• EPA Substance Registry System: 2,4-Hexanediol, 5-methyl-, (2R,4R)-rel-(36402-53-6)

Safety Data

• Hazardous Substances Data: 36402-53-6(Hazardous Substances Data)

Upstream product

• 65651-63-0 4-hydroxy-5-methyl-hexan-2-one 

Relevant articles and documents

INTRAMOLECULAR HYDROSILYLATIONS II: THE ANTI-SELECTIVE REDUCTION OF β-HYDROXYKETONES

A study was made of the synthesis and intramolecular hydrosilylation of silyloxyketones (2) (Sheme 2).It was found that with a variety of Lewis acid catalysts, anti-selective hydrosilylation took place to give (3) and, after desilylation, (5).With SnCl4, the most effective and practical catalyst, ratios (3):(4) ranged between 40:1 and 120:1 for a number of substrates.An explanation for the stereoselectivity is proposed based on (Cl) as a transition state model.The result is an anti-selective reduction of β-hydroxyketones, summarised in Scheme 4.