364079-44-7

Basic information

• Product Name: 4-(3-amino-7-morpholin-4-yl-6-phenyl-[1,8]naphthyridin-2-yl)-piperazine-1-carboxylic acid ethyl ester
• Synonyms: 4-(3-amino-7-morpholin-4-yl-6-phenyl-[1,8]naphthyridin-2-yl)-piperazine-1-carboxylic acid ethyl ester
• CAS NO: 364079-44-7
• Molecular Weight: 462.552
• Mol File: 364079-44-7.mol

Chemical Properties

• CAS DataBase Reference: 4-(3-amino-7-morpholin-4-yl-6-phenyl-[1,8]naphthyridin-2-yl)-piperazine-1-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-amino-7-morpholin-4-yl-6-phenyl-[1,8]naphthyridin-2-yl)-piperazine-1-carboxylic acid ethyl ester(364079-44-7)
• EPA Substance Registry System: 4-(3-amino-7-morpholin-4-yl-6-phenyl-[1,8]naphthyridin-2-yl)-piperazine-1-carboxylic acid ethyl ester(364079-44-7)

Safety Data

• Hazardous Substances Data: 364079-44-7(Hazardous Substances Data)

Upstream product

• 364079-43-6 4-(7-morpholin-4-yl-3-nitro-6-phenyl-[1,8]naphthyridin-2-yl)-piperazine-1-carboxylic acid ethyl ester 
• 120-43-4 4-ethoxycarbonylpiperazine 
• 326802-11-3 2-chloro-7-morpholin-4-yl-3-nitro-6-phenyl-[1,8]naphthyridine 

Relevant articles and documents

Synthesis and antiplatelet activity of some 2,7-di(N-cycloamino)-3-phenyl-1,8-naphthyridine derivatives

Several 2,7-di(N-cycloamino)-3-phenyl-1,8-naphthyridine derivatives were synthesized and tested for their ability to inhibit human platelet aggregation in vitro induced by arachidonic acid, collagen and ADP. Only five compounds showed any appreciable activity, and the results of all the active derivatives were similar to those of papaverine in the test with arachidonic acid and collagen. Moreover, the most active compounds were investigated in the test with ADP and again showed a significant activity. The tested compounds that possessed the best activity were also shown to increase the c-AMP level significantly without involving the adenylyl cyclase system. Copyright