3641-51-8Relevant articles and documents
Miniolins A-C, novel isomeric furanones induced by epigenetic manipulation of Penicillium minioluteum
Tang, Hao-Yu,Zhang, Qiang,Gao, Yu-Qi,Zhang, An-Ling,Gao, Jin-Ming
, p. 2185 - 2190 (2015/02/05)
Cultivation of Penicillium minioluteum with azacitidine, a DNA methyltransferase inhibitor, led to the isolation of a novel type of aspertetronin dimer, named miniolins A-C (1-3), along with their precursor aspertetronin A (4). The structures of 1-3 were elucidated by extensive spectroscopic methods, and the absolute configurations were assigned by the chiral HPLC analysis of chemical degradation products and electronic circular dichroism associated with the TDDFT computational method (CAM-B3LYP/TZVP). The miniolins showed moderate cytotoxic activity against Hela cell lines. This journal is
Assembly and absolute configuration of short-lived polyketides from burkholderia thailandensis
Ishida, Keishi,Lincke, Thorger,Hertweck, Christian
supporting information; experimental part, p. 5470 - 5474 (2012/07/14)
Decoded before decay: Cryptic and highly unstable polyketide metabolites, thailandamidesA and B, were isolated from Burkholderia thailandensis, and their absolute configurations fully elucidated using a combination of chemical degradation, bioinformatics, NMR spectroscopy, precursor-directed biosynthesis, and analysis of pathway intermediates (see scheme). Copyright
THE TOTAL SYNTHESIS OF PIPTOSIDIN
Poss, A. J.,Smyth, M. S.
, p. 5469 - 5472 (2007/10/02)
The synthesis of piptosidin, 2a, by the Michael addition of ascorbic acid to tigloyl cyanide is reported.