36431-73-9Relevant academic research and scientific papers
Biomimetic asymmetric total synthesis of (-)-laurefucin via an organoselenium-mediated intramolecular hydroxyetherification
Kim, Byungsook,Lee, Miseon,Mi, Jung Kim,Lee, Hyunjoo,Kim, Sanghee,Kim, Deukjoon,Koh, Minseob,Seung, Bum Park,Kye, Jung Shin
supporting information; experimental part, p. 16807 - 16811 (2009/04/14)
The first asymmetric total synthesis of (-)-laurefucin (1), a unique C-15 acetogenin with a 2,8-dioxabicyclo[5.2.1]decane skeleton, has been accomplished in nine steps in 31% overall yield from known oxocene 10. Highlights of the highly stereoselective synthesis include a novel organoselenium-mediated biomimetic hydroxyetherification.
Enzymatic Bromo-ether Cyclization of Laurediols with Bromoperoxidase
Fukuzawa, Akio,Aye, Mya,Takasugi, Yasunori,Nakamura, Masao,Tamura, Mamoru,Murai, Akio
, p. 2307 - 2310 (2007/10/02)
Natural (3E,6R,7R)-and (3Z,6S,7S)-laurediols were subjected to enzymatic reaction with the partially purified bromoperoxidase from the red alga, Laurencin nipponica, in the presence of H2O2 and NaBr to afford laurencia and prelaureatin, respectively.The further reaction of these products with bromoperoxidase gave rise to the bicyclic bromo-ethers.
Structure elucidation of laureoxanyne, a new nonisoprenoid C15 enyne, using lactoperoxidase
Fukuzawa
, p. 4895 - 4898 (2007/10/02)
The enzymatic structure elucidation of a minor bicyclic nonisoprenoid C15 enyne, laureoxanyne, isolated from the red alga Laurencia nipponica, is described.
