364356-61-6Relevant academic research and scientific papers
An insoluble polymer-bound bis-oxazoline copper(II) complex: A highly efficient heterogeneous catalyst for the enantioselective Mukaiyama aldol reaction
Orlandi, Simonetta,Mandoli, Alessandro,Pini, Dario,Salvadori, Piero
, p. 2519 - 2521 (2001)
The polystyrene-supported bis-oxazoline 1 forms a complex with copper(II)triflate that is a highly effective catalyst for the heterogeneously catalyzed enantioselective Mukaiyama aldol reaction of silylthioketene acetals with methyl pyruvate (ca. 90% yiel
Insoluble polystyrene-bound bis(oxazoline): Batch and continuous-flow heterogeneous enantioselective glyoxylate-ene reaction
Mandoli, Alessandro,Orlandi, Simonetta,Pini, Dario,Salvadori, Piero
, p. 3233 - 3244 (2007/10/03)
The use of a new, insoluble polymer-bound bis(oxazoline) ligand (IPB-box) for the copper-catalyzed heterogeneous enantioselective glyoxylate-ene reaction is described. Good activity and ee values in the range 85-95% have been obtained during five to seven recycles, either in batch mode or under flow conditions, demonstrating also the recovery and reuse of the whole catalytically active copper complex.
