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3644-61-9

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3644-61-9 Usage

Chemical Properties

White Solid

Originator

Tolperisone hydrochloride,Shanghai Abochem Chemical Co.

Uses

Tolperisone hydrochloride can be used as a muscle relaxant.

Manufacturing Process

To 1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanol in chloroform was added an excess of thionyl chloride and the reaction mixture refluxed until completed. It was then taken to dryness under reduced pressure and the residue crystallized by dissolving in hot alcohol and diluting with ethyl acetate. An aqueous solution of the obtained N-[3-chloro-3-(p-tolyl)propyl]piperidine hydrochloride was hydrogenated at 3 atmospheres in the presence of buffered palladium-on-charcoal catalyst. 1-Piperidino-2-methyl-3-(p-tolyl)-3-propanone was purified by distilling the base (boiling point 106-107°C/1 mm) and reconverting to the hydrochloride, melting point 216-217°C.

Therapeutic Function

Muscle relaxant, Vasodilator

Biochem/physiol Actions

Tolperisone is derived from piperidine and possesses membrane stabilizing action. It helps in reducing the effect of spasticities associated with the nervous and muscular system. It exhibits muscle relaxant action through attenuating voltage-gated sodium channels in the brain stem.

Check Digit Verification of cas no

The CAS Registry Mumber 3644-61-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,4 and 4 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3644-61:
(6*3)+(5*6)+(4*4)+(3*4)+(2*6)+(1*1)=89
89 % 10 = 9
So 3644-61-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H23NO.ClH/c1-13-6-8-15(9-7-13)16(18)14(2)12-17-10-4-3-5-11-17;/h6-9,14H,3-5,10-12H2,1-2H3;1H

3644-61-9 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • TCI America

  • (T1319)  Tolperisone Hydrochloride  >99.0%(HPLC)(T)

  • 3644-61-9

  • 25g

  • 580.00CNY

  • Detail
  • Sigma

  • (T3577)  Tolperisonehydrochloride  ≥98% (HPLC), solid

  • 3644-61-9

  • T3577-50MG

  • 1,141.92CNY

  • Detail
  • Sigma

  • (T3577)  Tolperisonehydrochloride  ≥98% (HPLC), solid

  • 3644-61-9

  • T3577-250MG

  • 4,574.70CNY

  • Detail

3644-61-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name Tolperisone hydrochloride

1.2 Other means of identification

Product number -
Other names 1-Propanone, 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-, hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3644-61-9 SDS

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