364594-65-0Relevant articles and documents
Synthesis and in vivo evaluation of phenethylpiperazine amides: Selective 5-hydroxytryptamine2A receptor antagonists for the treatment of insomnia
Xiong, Yifeng,Ullman, Brett,Choi, Jin-Sun Karoline,Cherrier, Martin,Strah-Pleynet, Sonja,Decaire, Marc,Dosa, Peter I.,Feichtinger, Konrad,Teegarden, Bradley R.,Frazer, John M.,Yoon, Woo H.,Shan, Yun,Whelan, Kevin,Hauser, Erin K.,Grottick, Andrew J.,Semple, Graeme,Al-Shamma, Hussien
experimental part, p. 5696 - 5706 (2010/10/18)
Recent developments in sleep research suggest that antagonism of the serotonin 5-HT2A receptor may improve sleep maintenance insomnia. We herein report the discovery of a series of potent and selective serotonin 5-HT2A receptor antag
PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
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Page/Page column 82, (2008/06/13)
Pyrazole derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the serotonin 5HT2A receptor. Formula (Ia). Compounds and pharmaceutical compositions thereof are directed to methods useful in the treat